| [1]Schaeffer S M,Nakata P A.The expanding footprint of CRISPR/Cas9 in the plant sciences J.Plant Cell Rep,2016,35 (7):
1451-1468.
[2]李莉，毕延震，华再东，郑新民，等。基因编辑技术及其在畜牧业中的应用研究进展[J].基因组学与应用生物学，2016，35(12)：3410-3418.
[3]Wang H,La Russa M,Qi L S.CRISPR/Cas9 in Genome Editingand Beyond [J].Annu Rev Biochem,2016,85:227-264.
[4]Yu-yun Xing,Qiang Yang,Jun Ren.Application of CRISPR/Cas9 mediated genome editing in farm animals J].Yi Chuan,2016,38(3)：217-226.
[5]魏楠，谷峰.CRISPR/Cas9技术在猪常见病毒性疾病防控中的应用J].中国兽医学报，2021,41(02)：366-372.
[6]Gupta D,Bhattacharjee O,Mandal D,et al.CRISPR-Cas9 sys-tem:A new-fangled dawn in gene editing J.Life sciences,2019,232:116636.
[7]Carroll D.Genome engineering with zinc-finger nucleases J].Genetics,2011,188(4):773-782.
[8]Mali P,Yang L,Esvelt K M,Aach J,Guell M,DiCarlo J E,Church G M.RNA-guided human genome engineering via Cas9J].Science,2013,339(6121):823-826.
[9]Whitworth K M,Rowland RR,Ewen C L,Trible B R,KerriganM A,Cino-Ozuna A G,Samuel M S,Lightner J E,McLaren DG,Mileham A J.Gene-edited pigs are protected from porcine re-productive and respiratory syndrome virus J.Nat Biotechnol,2016,34（1)：20-22.
[10]Proudfoot C,Carlson D F,Huddart R,Long C R,Pryor J H,King T J,Lillico S G,Milcham A J,McLaren D G,Whitclaw CB A.Genome edited sheep and cattle J.Transgenic Research,2015,24：147-153.
[11]Guo R,Wan Y,Xu D,Cui L,Deng M,Zhang G,Jia R,Zhou W,Wang Z,Deng K.Generation and evaluation of Myosta-tin knock-out rabbits and goats using CRISPR/Cas9 system [J].Scientifc Reports.2016.6:1-10.
[12] Reyes L M,Estrada J L,Wang Z Y,Blosser R J,Smith R F,Sidner R A,Paris LL,Blankenship R L,Ray C N,Miner A C.Creating class I MHC-null pigs using guide RNA and the Cas9 en-donuclease [J].The Journal of Immunology,2014,193:5751-5757.
[13]Park Y H,Chungu K,Lee S B,et al.Host-specific restrictionof avian influenza virus caused by differential dynamics of ANP32family members J].J.Infect.Dis,2020,221:71-80.
[14]Blyth G A D,Chan W F,Webster R G,Magor K E.Duck inter-feron-inducible transmembrane protein 3 mediates restriction of in-fluenza viruses [J].J.Virol,2020,90:103-116.
[15]Lee J,Ma J,Lee K.Direct delivery of adenoviral CRISPR/Cas9vector into the blastoderm for generation of targeted gene knockoutin quail[J].Proc.Natl.Acad.Sci.U.S.A,2020,27:13288-13292.
[16]Lee J,Kim D H,Lee K.Muscle hyperplasia in Japanese quail bysingle amino acid deletion in MSTN propeptide [J].Int.J.Mol.Sci,2020,21:1504.
[17]Gao Y,Wu H,Wang Y,Liu X,Chen L,Li Q,Cui C,LiuX,Zhang J,Zhang Y.Single Cas9 nicks induced generation ofNRAMPI knock in cattle with reduced of target effects J].Ge-nome Biology,2017,18:1-15.
[18]Ikeda M,Matsuyama S,Akagi S,Chokshi K,Nakamura S,Minable S,Kimura K,Hosoi M.Harnessing endogenous repairmechanisms for targeted gene knock-in during preimplantation de-velopment of bovine embryos J.Scientific Reports,2020,7:1-9.
[19]Zhang X,Li W,Liu C,Peng X,Lin J,He S,Li X,Han B,Zhang N,Wu Y.Alteration of sheep coat color pattern by disrup-tion of ASIP gene via CRISPR-Cas9 J].Scientific Reports,2017,7:1-10.
[20]Williams D K,Pinzon C,Huggins S,Pryor J H,Falck A,Herman F,Olde Schulte J,Chavez M B,Foster B L,White SH.The DREADD agonist clozapine N-oxide (CNO)is reverse-metabolized to clozapine and produces clozapine-like interoceptivestimulus effects in rats and mice [J].Scientific Reports,2018,8:1-10.
[21]Crispo M,Mulet A,Tesson L,Barrera N,Cuadro F,dos San-tos-Neto P,Nguyen T,Creneguy A,Brusselle L,Anegon I.Efcient generation of myostatin knock-out sheep using CRISPR/Cas9 technology and microinjection into zygotes [J].PLoS ONE,2015,10:e0136690.
[22]WangX,Yu H,Lei A,Zhou J,Zeng W,Zhu H,Dong Z,Niu Y,Shi B,Cai B.Generation of gene-modifed goats targetingMSTN and FGF5 via zygote injection of CRISPR/Cas9 system J].Scientife Reports,2015,5:1-9.
[23]Tian H,Luo J,Zhang Z,Wu J,Zhang T,Busato S,HuangL,Song N,Bionaz M.CRISPR/Cas9-mediated Stearoyl-CoADesaturase 1 SCDI defciency afects fatty acid metabolism ingoat mammary epithelial cells [J].Journal of Agricultural andFood Chemistry,2018,66:10041-10052.
[24]吴言，郝雅荞，韦璇，沈琦，柳叶飞，王升厚，赵洪新.新一代精准基因编辑工具CRISPR/Cas9的技术优势与应用局限[J].生物技术通报，2018(05)：1-8.
[25]Katsuma S,Shoji K,Suzuki Y,Kiuchi T.CRISPR/Cas9-medi-ated mutagenesis of Ago2 and Siwi in silkworm cultured cells J].Gene,2021,768:145314. |
